VANCOMYCIN HCL
  STERILE
 
           L-PHENYLALANINE  
          COLISTIN SULPHTE  
           COLISTIN SULFATE
   PREMIX 10%
 
 
 
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【Active ingredients】Colistin sulfate 

Structural formula
 MOA/IOA→(α)DAB→Thr →(α)DAB→(α)DAB→(α)DAB→D-Leu→L-Leu
                                                            ↑γ                   ↓
                                                                    Thr ←(α)DAB ← (α)
                  D

Chemical formula & Molecular weight
Colistin A: C53H100N16O13         1169
Colistin B: C52H98N16O13          1155

Method for preparation
Colistin sulfate premix is elaborated through a combination of  soybean bran pure as the carrier and Colistin sulfate technical. It makes the feature of an even distribution of the active ingredients and fine stability.

Indications for use

It is intended for the inhibition of Gram-negative bacteria as a somatomedin either in breeding period or quiescence against intestine diseases caused by Gram-negative bacteria such as colibacillus and pseudomonas aeruginosa. When added into Feed, it exerts positive effects on the growth promotion and the increase of Feed utility rate.

Principle
The positive free amino group of the active ingredients is combined with the negative polyphosphate in the cell membrane as well as with nucleic acid to form insoluble compounds, resulting in cell membrane damage, permeability improvement of cell membrane and leakage of intracellular phosphate and nucleic acid to kill bacteria.

Indications for use and dosage
Mix thoroughly with Feed in a gradient scale, calculated with the reference to the dosage per ton.
【Package】25kgs/bag

 
 

 

 
 
 

 

 
 
 

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